The Scitech memory profiler has quite a basic UI but lots of useful information, including some information on unmanaged memory which dotTrace and ANTS lack - you might find it useful if you are doing COM interop, but I have yet to find any profiler that makes COM memory issues easy to diagnose - you usually have to break out windbg.exe.
The ANTS profiler has come on in leaps and bounds in the last few years, and its memory profiler has some truly useful features which now pushed it ahead of dotTrace as a package in my estimation. I'm lucky enough to have licenses for both, but if you are going to buy one .Net profiler for both performance and memory, make it ANTS.
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Both ANTS and the Scitech memory profiler have features that the other doesn't, so which is best will depend upon your preferences. Generally speaking, the Scitech one provides more detailed information while the ANTS one is really incredible at identifying the leaking object. Overall, I prefer the ANTS one because it is so quick at identifying possible leaks.
While not yet as full-featured as some of the other .NET memory profilers listed here, there is a new entry on the market called JustTrace. It's made by Telerik and it's primary goal is to make tracing/profiling easier and faster to do for all types of apps (web/Silverlight/desktop).
The latest version of ANTS memory profiler (I think it's 5) simply rocks!!! I was haunting a leak using WinDbg and SOS since it proved to be the best way before, then I tried ANTS and I got it in minutes. Really a wonderful piece of software.
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